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Splicing machinery dysfunctions have been associated to CLL
2019-06-24
Splicing machinery dysfunctions have been associated to CLL, in particular gene mutations (splicing factor 3B subunit 1) which are present in about 15% of patients . To our knowledge, no gene mutation has ever been detected in CLL. In order to broaden our knowledge on the frequency of splicing mu
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Flow cytometric immunophenotyping showed the circulating bla
2019-06-24
Flow cytometric immunophenotyping showed the circulating blasts expressed CD19, CD20, CD22, CD24 partial, HLA -DR, CD34, and TdT. There was variable expression of the myeloid markers CD15 and CD33. The blasts were negative for CD3, CD10, MPO, and all other T-cell, myeloid, and monocytic markers eval
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However Ethiopia is addressing this
2019-06-24
However, Ethiopia is addressing this situation head-on. To increase access to oxygen and pulse oximetry, the Ethiopian Ministry of Health (MOH) has responded by undertaking a comprehensive strategic planning process captured as a roadmap for oxygen and pulse oximetry scale-up. A national technical w
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br Current approaches to HIV prevention typically target peo
2019-06-24
Current approaches to HIV prevention typically target people who are identified as, or self-identify, with being at risk. In Africa, 74% of new HIV infections are among adolescent girls aged 15–19 years, and AIDS-related illnesses are the leading cause of death among adolescent girls and women of
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antioxidant Numerous clinical trials phase II and
2019-06-24
Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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Initial radiographs demonstrated an aggressive lesion in
2019-06-24
Initial radiographs demonstrated an aggressive lesion in the medial condyle of the distal right femur (Figs. 1A and B). CT obtained to characterize matrix showed an aggressive lesion with a focus of dense linear matrix (Fig. 2) with intervening lucent areas. The lesion was felt to be indeterminate a
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To better understand how the unpaid status of internships at
2019-06-24
To better understand how the unpaid status of internships at WHO headquarters might affect their international accessibility, together with past and present intern colleagues, we did an online survey during two summer intern cohorts (2011 and 2013). The survey, which was distributed via email to all
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Some health related topics are guaranteed to stir up heated
2019-06-24
Some health-related topics are guaranteed to stir up heated debate in the general public whenever they lipid metabolism crop up in the news. Publishing a research paper on chronic fatigue syndrome, homoeopathy, or mode of childbirth is a recipe for a media field day, a lively letters section, and a
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Volvemos nosotros a tomar el hilo El proyecto en
2019-06-24
Volvemos nosotros Ki16198 what tomar el hilo. El proyecto en cuestión remonta a las de Michel chevalier, publicadas en París en 1836, y que ya circulaban en chile al menos desde 1842. Para la llegada de Bilbao a Francia en 1845, el libro de chevalier era todo un éxito editorial. Había alcanzado en
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M s adelante del fragmento arriba
2019-06-24
Más adelante del fragmento arriba citado de Memórias, hallamos otro en el que se aborda la cuestión de la insensibilidad. Graciliano la juzga extraña al igual que extraordinaria le parece la desaparición de los deseos sexuales: afirma que todos los sentidos desfallecían. Si son los sentidos los que
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En Por qu construir un pueblo es la tarea
2019-06-24
En “\"Por qué construir un pueblo es la tarea de la política radical?”, Laclau profundiza una tensión en su teoría en el marco de la respuesta Tenovin-3 Slavoj zžek. Por un lado, la formalidad de la lógica populista, en principio, impide predicar sus alcances en cuanto a la democracia (tanto en un s
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Currently RFCA is indicated if pharmacologic therapies are u
2019-06-24
Currently, RFCA is indicated if pharmacologic therapies are unsuccessful [41]. Myocardial substrates for reentrant VT and/or the origin of focal VT are the ablation target for monomorphic VT storms. Although ablating multiple and unstable VTs is challenging, modern computerized mapping and catheter
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br Vascular cells and the peribiliary
2019-06-21
Vascular cells and the peribiliary vascular plexus The liver is a highly vascularized organ that receives dual blood supplies from the hepatic portal vein (HPV) and hepatic order CB-839 (Fig. 1). The HPV delivers approximately 75% of the total blood supply that the liver receives and carries from
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Vollmer and colleagues distinctive multilevel modelling has
2019-06-21
Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau
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En ella se muestran los criterios
2019-06-21
En ella se muestran los criterios sobre los que se acepta negociar en los diálogos de paz en La Habana. Fuera de estas reglas de juego para la negociación, se establecen puntos en común en ella y que según Aira: “Es indiscutible que el ‘Poder’ desempeña un papel fundamental dentro de la negociación”
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