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br Introduction br Rac dependent ROS and actin regulation in
2024-04-28
Introduction Rac1-dependent ROS and atp gamma s sale regulation in neuronal functions NOX-mediated ROS have an important role as physiological messengers. One remarkable example regarding such a function is during axonal formation. In this line, increased p40phox/NOX2 levels and co-localizati
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To date the molecular responses of
2024-04-28
To date, the molecular responses of AChE have been partially analyzed in its mRNA level or protein activity in aquatic animals. To understand the correlation between transcriptional change and activity of AChE, we conducted both experiments in B. koreanus. Generally, the DNA Damage DNA Repair Librar
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br Conflict of interest br Acknowledgments br Introduction
2024-04-28
Conflict of interest Acknowledgments Introduction Inflammation is a protective response of the microcirculation to harmful stimuli. Yet, excessive inflammation is potentially harmful and a characteristic of many chronic diseases [1]. 5-Lipoxygenase (5-LO, EC1.13.11.34) contributes to the in
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br Introduction The process of mitosis is
2024-04-27
Introduction The process of mitosis is highly complex and tightly regulated. This phase of the SYBR Safe DNA Gel Stain resulted in two identical daughter cells. The aurora kinases (aurora A, B, and C) are a family of three highly homologous serine-threonine protein kinases that play a key role i
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Beside estrogen several classes of
2024-04-27
Beside estrogen, several ampk pathway of compounds have shown significant neuroprotective efficacy when administered shortly after the induction of animal models of stroke, including glutamate (NMDA) receptor antagonists and zinc chelators [25], [26], [27]. Effects of these or other neuroprotective
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To clarify the molecular mechanism of maduramicin induced ap
2024-04-27
To clarify the molecular mechanism of maduramicin-induced apoptosis in chicken myocardial cells, the mRNA levels of bcl-2, bax, and cytochrome C, as well as the mRNA levels and activities of caspase-3/8/9 were determined. The mRNA expressions and activities of initiator casapase-9 and executioner ca
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br ROS in AiP and regeneration Tissue wounding and inflammat
2024-04-27
ROS in AiP and regeneration Tissue wounding and inflammation are associated with production of ROS, and recent studies show that generation of ROS, especially during the initial stages of wounding and regeneration are essential for an efficient wound healing response. ROS, in particular H2O2 func
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Obesity is associated with chronic low grade inflammation
2024-04-27
Obesity is associated with chronic low-grade glibenclamide resulting from increased M1 macrophage infiltration into adipose tissue, which can subsequently lead to the development of insulin resistance. Previously, we reported that LFE and FSB both reduced body weight gain in high fat diet-induced ob
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br Acknowledgements br Introduction The angiogenic ocular co
2024-04-27
Acknowledgements Introduction The angiogenic ocular conditions represent the most common cause of blindness in developed countries [1]. It can affect all ages, for example, retinopathy of prematurity (ROP) in infants [2], [3], diabetic retinopathy (DR) [4] in working age adults and age-related
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AR Vs are truncated AR
2024-04-27
AR-Vs are truncated AR proteins lacking the AR ligand-binding domain (AR-LBD) [6]. While AR-Vs have frequently been detected in CRPC, their expression and functional role in benign prostate tissues and primary prostate cancers is not readily apparent. Structural rearrangements in the AR gene and alt
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Because of the critical roles played by
2024-04-27
Because of the critical roles played by AMPK in energy sensing and cancer cell survival, a huge number of drugs have been proposed to exert their pharmacological effects by means of AMPK activation (Kim and He, 2013). For example, metformin has been shown to activate AMPK in muscle (Sajan et al., 20
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To validate the identified phosphorylation
2024-04-27
To validate the identified phosphorylation sites in the mouse heart, we analyzed HEK 293T Cy5.5 hydrazide transfected with Adrb1 based on the hypothesis that protein residues phosphorylated both in vivo and in vitro are more likely to be physiologically relevant. All of the phosphorylation sites id
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Obesity is defined as a body
2024-04-27
Obesity is defined as a body mass index (BMI) of 30kg/m2 or higher and is known to have a very close association with the risk of developing cancers (Hsueh and Deng, 2016). Several theories exist as to how this link is defined with respect to various cancers, one of which involves the effect of obes
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PAN induced nephrosis was accompanied by loss
2024-04-26
PAN-induced nephrosis was accompanied by loss of body weight, decrease of food intake, increase in urine volume and increases in triglycerides and cholesterol levels, which have been reported previously (Natori et al., 1996). Except for urine volume, each one of these measures was improved by A-3069
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Children with ADA SCID commonly suffer from a variety of
2024-04-26
Children with ADA-SCID commonly suffer from a variety of opportunistic infections, including viral, fungal, and mycobacterial infections. Due to defects in mass to moles calculator and IG production, they are also susceptible to infection with encapsulated bacteria such as Haemophilus influenzae, S
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